Symbia Pro.specta SPECT/CT

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Symbia Pro.specta SPECT/CT¹ helps accelerate decision-making with fast imaging at every stage—from preparation to diagnosis. Designed with theranostics at its core, Symbia Pro.specta empowers personalized care by seamlessly integrating imaging and therapy. It’s your all-in-one solution for managing complexities in oncology, cardiology, neurology, and beyond.

Fast - Quick and efficient scans
Precise - Consistent, reproducible results
Flexible - Clinical and operational versatility
Future-ready - Customizable configurations and easy upgradability

Benefits

Can you meet the rising demand for nuclear medicine imaging without compromising quality or efficiency? With Symbia Pro.specta, you can.

Thanks to intelligent imaging and fast acquisitions, Symbia Pro.specta completes scans quickly and efficiently without compromising quality or safety. Fast, low-dose scans, and rapid results help you accelerate patient throughput while delivering the best possible care.

Data courtesy of Nebraska Cancer Specialists, Omaha, Nebraska, USA.

Offering dedicated collimators, automatic motion correction, and advanced reconstruction tools, Symbia Pro.specta raises the bar with precise SPECT/CT quantification—so you can detect and measure what matters with clarity and confidence.

Symbia Pro.specta supports a broad range of clinical needs. It performs all nuclear medicine scans, including theranostics, and covers all energies up to 588 keV. Benefit from flexible imaging protocols, comprehensive radiopharmaceutical support, and design for patients of all mobility levels and up to 500 lb (227 kg).

With its versatile design and flexible configuration options, Symbia Pro.specta expands clinical offerings without increasing its physical footprint.² Upgradeable features ensure your investment continues to deliver value as technologies and opportunities advance.

Evidence

See what’s possible when you can customize your SPECT/CT scanner with technologies that automatically optimize image quality and workflow for cardiology, oncology, neurology theranostics, and much more.

Symbia Pro.specta Theranostics Clinical Case 3

^{Data and images courtesy of Unithera, Glen Burnie, Maryland, USA.}

10-minute whole-body SPECT/CT with xSPECT Quant for ¹⁷⁷Lu-PSMA therapy response assessment

SPECT
Scan acquisition: 2 bed positions/60 stops per detector; 30 min WB study: 15 seconds per stop; 10 min WB study: 5 seconds per stop; Image reconstruction: 128 x 128 matrix, OSCGMM 24/4s; Injected dose: 177Lu PSMA 197 mCi (7300 MBq)

CT
Scan parameters: 110 kVSn/40 ref mAs 0.8 sec rotation; 32 x 0.7 mm collimation, 5 mm recon

MI Symbia Pro.specta Theranostics Clinical Case 1

^{Data courtesy of Queen Elizabeth Hospital Birmingham, Birmingham, UK.}

Whole-body SPECT/CT in post-surgery thyroid cancer after ablative ¹³¹I therapy demonstrates residual thyroid

SPECT
Scan acquisition: 3 bed positions/60 stops per detector, 7 seconds per stop; Image reconstruction: 128 x 128 matrix, OSEM3D, 24i4s; Injected dose: Iodine 131 (¹³¹l) 29 mCi (1,100 MBq)

CT
Scan parameters: 130 kV/13 ref mAs

Symbia Pro.specta SPECT/CT with myExam Companion Clinical Images

^{Data courtesy of Queen Elizabeth Hospital Birmingham, Birmingham, UK.}

Fast IQ•SPECT cardiac acquisition delineates normal myocardial perfusion at stress and rest

SPECT
Scan acquisition: IQ•SPECT, step-and-shoot method, 22 seconds per stop, 17 stops per detector; Total scan time: 6.2 minutes; Image reconstruction: 128 x 128 matrix, OSCGM, 48i1s, Gaussian filter 10; CT attenuation correction (CTAC); Injected dose: ^99mTc-Myoview (dose amount anonymized)

CT
Scan parameters: 120 kV/56 ref mAs

^{Data courtesy of Queen Elizabeth Hospital Birmingham, Birmingham, UK.}

iMAR improves biliary drainage catheter visualization in ^99mTc-HIDA SPECT/CT following liver tumor embolization

SPECT
Scan acquisition: 60 stops per detector, 10 seconds per stop; Image reconstruction: 128 x 128 matrix, OSEM3D, 24i4s; Injected dose: ^99mTc-HIDA 3.8 mCi (142 MBq)

CT
SAFIRE
Scan parameters: 120 kV/40 ref mAs, 0.33-sec rotation, 32 x 0.7-mm collimation, 2-mm recon, BR40 S3 iMAR²

^{Data courtesy of Baylor Scott, White Medical Center, Temple, Texas, USA.}

Parathyroid adenoma defined on ^99mTc-MIBI SPECT/CT

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Scan acquisition: 1 bed position/48 stops per detector, 25 seconds per stop; Image reconstruction: 128 x 128 matrix, OSEM3D, 24i4s; Injected dose: ^99mTc-Sestamibi (dose amount anonymized); Post-injection delay: 2 hours

CT
SAFIRE
Scan parameters: 110 kV/90 ref mAs, 0.8-sec rotation, 32 x 0.7-mm collimation, 5-mm recon, Qr40S3

^{Data courtesy of Queen Elizabeth Hospital Birmingham, Birmingham, UK.}

¹¹¹In-Octreotide 4- and 24-hour planar and SPECT/CT study shows increasing uptake in para-aortic metastases

SPECT
Scan acquisition: 2 bed positions/60 stops per detector, 15 seconds per stop; Image reconstruction: 128 x 128 matrix, Flash3D, 18i4s; Injected dose: ¹¹¹In-Octreotide 4.7 mCi (176 MBq); Post-injection delay: 4 and 24 hours

CT
SAFIRE
Scan parameters: 120 kV/213 ref mAs, 0.33-sec rotation, 32 x 0.7-mm collimation, 1.5-mm recon, BR40 S3

^{Data courtesy of Queen Elizabeth Hospital Birmingham, Birmingham, UK.}

Bilateral reduction in striatal dopaminergic receptor density defined on SPECT/CT with ratio analysis

SPECT
Scan acquisition: Low-energy high-resolution (LEHR), step-and-shoot method, 40 seconds per view; Image reconstruction: OSEM3D, 10i8s, Gaussian filter 8; Injected dose: ¹²³I-Ioflupane 4.9 mCi (182.40 MBq)

CT
Scan parameters: 110 kV/24 ref mAs

^{Data courtesy of Queen Elizabeth Hospital Birmingham, Birmingham, UK.}

Bone SPECT/CT defines site of fracture of vertical spinal stabilization rod at level of L5 vertebral pedicle

SPECT
Scan acquisition: 3 bed positions/60 stops per detector, 10 seconds per stop; Image reconstruction: 128 x 128 matrix, OSEM3D, 7i15s; Injected dose: ^99mTc-HMDP 20.9 mCi (776 MBq); Post-injection delay: 2 hours

CT
SAFIRE
Scan parameters: 130 kV/30 ref mAs, 0.33-sec rotation, 32 x 0.7-mm collimation, 1.5-mm recon, BR40 S3

Read the complete clinical case study

^{Data courtesy of Queen Elizabeth Hospital Birmingham, Birmingham, UK.}

xSPECT Bone and CT with iMAR define reactive bony sclerosis in tibial malunion following plate fixation

SPECT
Scan acquisition: 60 stops per detector, 20 seconds per stop; Image reconstruction: 128 x 128 matrix, xSPECT Bone; Injected dose: ^99mTc-HMDP 16.3 mCi (603 MBq); Post-injection delay: 3 hours

CT
SAFIRE
Scan parameters: 120 kV/150 ref mAs, 0.33-sec rotation, 32 x 0.7-mm collimation, 1-mm recon, BR44 S3 iMAR²

^{Data courtesy of Queen Elizabeth Hospital Birmingham, Birmingham, UK.}

xSPECT Bone and xSPECT Quant with iMAR CT define loosening of tibial component in right knee arthroplasty

SPECT
Scan acquisition: 30 stops per detector, 20 seconds per stop; Image reconstruction: 128 x 128 matrix, xSPECT Bone; Injected dose: ^99mTc-HMDP 15.6 mCi (578 MBq); Post-injection delay: 3 hours

CT
SAFIRE
Scan parameters: 110 kV/181 ref mAs, 0.33-sec rotation, 32 x 0.7-mm collimation, 1-mm recon, BR44 S3 iMAR²��

Read the complete clinical case study

^{Data and images courtesy of Unithera, Glen Burnie, Maryland, USA.}

10-minute whole-body SPECT/CT with xSPECT Quant for ¹⁷⁷Lu-PSMA therapy response assessment

CT
Scan parameters: 110 kVSn/40 ref mAs 0.8 sec rotation; 32 x 0.7 mm collimation, 5 mm recon

^{Data courtesy of Queen Elizabeth Hospital Birmingham, Birmingham, UK.}

Whole-body SPECT/CT in post-surgery thyroid cancer after ablative ¹³¹I therapy demonstrates residual thyroid

SPECT
Scan acquisition: 3 bed positions/60 stops per detector, 7 seconds per stop; Image reconstruction: 128 x 128 matrix, OSEM3D, 24i4s; Injected dose: Iodine 131 (¹³¹l) 29 mCi (1,100 MBq)

CT
Scan parameters: 130 kV/13 ref mAs

^{Data courtesy of Queen Elizabeth Hospital Birmingham, Birmingham, UK.}

Fast IQ•SPECT cardiac acquisition delineates normal myocardial perfusion at stress and rest

CT
Scan parameters: 120 kV/56 ref mAs

^{Data courtesy of Queen Elizabeth Hospital Birmingham, Birmingham, UK.}

iMAR improves biliary drainage catheter visualization in ^99mTc-HIDA SPECT/CT following liver tumor embolization

SPECT
Scan acquisition: 60 stops per detector, 10 seconds per stop; Image reconstruction: 128 x 128 matrix, OSEM3D, 24i4s; Injected dose: ^99mTc-HIDA 3.8 mCi (142 MBq)

CT
SAFIRE
Scan parameters: 120 kV/40 ref mAs, 0.33-sec rotation, 32 x 0.7-mm collimation, 2-mm recon, BR40 S3 iMAR²

^{Data courtesy of Baylor Scott, White Medical Center, Temple, Texas, USA.}

Parathyroid adenoma defined on ^99mTc-MIBI SPECT/CT

CT
SAFIRE
Scan parameters: 110 kV/90 ref mAs, 0.8-sec rotation, 32 x 0.7-mm collimation, 5-mm recon, Qr40S3

^{Data courtesy of Queen Elizabeth Hospital Birmingham, Birmingham, UK.}

¹¹¹In-Octreotide 4- and 24-hour planar and SPECT/CT study shows increasing uptake in para-aortic metastases

CT
SAFIRE
Scan parameters: 120 kV/213 ref mAs, 0.33-sec rotation, 32 x 0.7-mm collimation, 1.5-mm recon, BR40 S3

^{Data courtesy of Queen Elizabeth Hospital Birmingham, Birmingham, UK.}

Bilateral reduction in striatal dopaminergic receptor density defined on SPECT/CT with ratio analysis

CT
Scan parameters: 110 kV/24 ref mAs

^{Data courtesy of Queen Elizabeth Hospital Birmingham, Birmingham, UK.}

Bone SPECT/CT defines site of fracture of vertical spinal stabilization rod at level of L5 vertebral pedicle

CT
SAFIRE
Scan parameters: 130 kV/30 ref mAs, 0.33-sec rotation, 32 x 0.7-mm collimation, 1.5-mm recon, BR40 S3

Read the complete clinical case study

^{Data courtesy of Queen Elizabeth Hospital Birmingham, Birmingham, UK.}

xSPECT Bone and CT with iMAR define reactive bony sclerosis in tibial malunion following plate fixation

CT
SAFIRE
Scan parameters: 120 kV/150 ref mAs, 0.33-sec rotation, 32 x 0.7-mm collimation, 1-mm recon, BR44 S3 iMAR²

^{Data courtesy of Queen Elizabeth Hospital Birmingham, Birmingham, UK.}

xSPECT Bone and xSPECT Quant with iMAR CT define loosening of tibial component in right knee arthroplasty

CT
SAFIRE
Scan parameters: 110 kV/181 ref mAs, 0.33-sec rotation, 32 x 0.7-mm collimation, 1-mm recon, BR44 S3 iMAR²��

Read the complete clinical case study

Offering dedicated collimators, automatic motion correction, and advanced reconstruction tools, Symbia Pro.specta raises the bar with precise SPECT/CT quantification—so you can detect and measure what matters with clarity and confidence. — Data courtesy of United Theranostics, Glenburnie, Maryland, USA.

Optimized imaging for theranostics

Every Symbia Pro.specta system is theranostics-ready and features the only SPECT crystal technology clinically proven to manage all SPECT energies reliably, and collimators specifically designed for each isotope.³^��These technologies, together with quantification solutions that are precise and reproducible, give you full theranostics capabilities.

Learn more

Customer voices

Symbia Pro.specta users share their insights about image quality, ease of use, dose reduction, clinical versatility, and more.

“The radiologists loved the images with SAFIRE, and it also helped lower the doses.” ⁵

Erin Ross, PhD

Consultant, clinical scientist and
deputy head of nuclear medicine
Queen Elizabeth Hospital Birmingham, Birmingham, UK

The Symbia Pro.specta in Helsinki was installed in 2022 as the second in Europe for clinical use. “I think it was exciting for us all,” said Reijonen.

Growing theranostics program is now everyday clinical practice in Finland

The Comprehensive Cancer Center in Helsinki offers precision therapy personalized to the needs of each patient. Symbia Pro.specta plays a key role in imaging-enabled treatment evaluation.

Expand your imaging capabilities

Customize your system with dedicated clinical tools that automatically optimize image quality and workflow for cardiology, oncology, neurology, and more.

Technical Details

Technical Specifications

Bore diameter: 70 cm
Tunnel length: 106.4 cm

Technical Specifications

Slices: 32/64⁶
Rotation time: up to 0.33 s⁶
Tube: up to 7.0 MHU⁶ (17.5 MHU equivalent value with SAFIRE⁷)
Power: up to 75 kW⁶ (187 kW equivalent value with SAFIRE⁷)
High voltage: up to 70-140 kv⁶ (10kV steps)
mA: up to 825 mA⁶ (2.06 A equivalent value with SAFIRE⁷)
Iterative reconstruction: SAFIRE⁷
Low-dose scanning: Tin Filter
Metal artifact reduction: iMAR4^4,8

Technical Specifications

Crystal thickness: 3/8” or 5/8”
Detector dimension (FoV): 53.3 x 38.7 cm
Energy range: 35-588 keV
System sensitivity (LEHR at 10 cm): 202 cpm/μCi
Acquisition modes: Static, dynamic, gated, SPECT, gated SPECT,
dynamic SPECT, composite SPECT,
whole-body, whole-body SPECT, SPECT/CT
Quantitative accuracy: ≤ 5%⁹

Downloads

Siemens Healthineers Symbia pro.Specta brochure frontpage

Learn more about Symbia Pro.specta

Symia Pro.specta SPECT/CT is not commerically available in all countries. Future availability cannot be guarenteed.

Compared with other Siemens Healthineers SPECT-only systems.

Based on competitive literature at time of publication. Data on file.

iMAR is designed to yield images with a reduced level of metal artifacts compared to conventional reconstruction if the underlying CT data is distorted by metal being present in the scanned object. The exact amount of metal artifact reduction and the corresponding improvement in image quality achievable depends on a number of factors, including composition and size of the metal part within the object, patient size, anatomical location, and clinical practice. It is recommended to perform iMAR reconstruction in addition to conventional reconstruction.

The statements by Siemens Healthineers customers described herein are based on results that were achieved in the customer's unique setting. Because there is no "typical" hospital or laboratory and many variables exist (eg, hospital size, samples mix, case mix, level of IT, and/or automation adoption), there can be no guarantee other customers will achieve the same results.

Dependent on configuration.

In clinical practice, the use of SAFIRE may reduce CT patient dose depending on the clinical task, patient size, anatomical location, and clinical practice. A consultation with a radiologist and a physicist should be made to determine the appropriate dose to obtain diagnostic image quality for the particular task.

Optional.

Data on file.

Contact

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Symbia Pro.specta with myExam CompanionYour faster way to answers.

Benefits

Evidence

10-minute whole-body SPECT/CT with xSPECT Quant for 177Lu-PSMA therapy response assessment

Optimized imaging for theranostics

Customer voices

​Growing theranostics program is now everyday clinical practice in Finland

Intelligent Imaging

Expand your imaging capabilities

Intelligent cardiology imaging

Intelligent oncology imaging

​Intelligent neurology imaging

Technical Details

Related Topics

Explore more

myExam Companion

Clinical versatility

Symbia SPECT/CT innovation

Downloads

Learn more about Symbia Pro.specta

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10-minute whole-body SPECT/CT with xSPECT Quant for ¹⁷⁷Lu-PSMA therapy response assessment

Growing theranostics program is now everyday clinical practice in Finland

Intelligent neurology imaging